Various studies have shown that over 20% of people have suboptimal (borderline) levels of vitamin B12, which may not be sufficient to meet individual metabolic needs. Depending on the study and the study group, borderline levels of B12 are observed in far higher proportions – even up to 80%! There are actually four different forms of vitamin B12, collectively called “cobalamins”. Cobalamin is an extremely complex organometallic compound with a central cobalt ion, which has been described as “nature’s most beautiful cofactor”. The two most bioavailable and naturally occurring forms are methylcobalamin and adenosylcobalamin. These are the real stars of the vitamin B12 team, both of which act intracellularly, but at different sites. Each has its own strengths, but the real magic happens when they are taken together – as is the case with Vimergy® Organic Liquid Vitamin B12 .
Methylcobalamin
- The most active and most bioavailable form of B12, found primarily in intracellular fluid (cytosol), other body fluids, and in the brain, as it can cross the blood-brain barrier.
- A great form for people with delayed detoxification processes or impaired methylation. The “methyl” group in methylcobalamin is one of the most miraculous and important molecules in the body. From protecting DNA to aiding detoxification, methyl groups are used in a variety of methylation processes. Methylation, for example, is one of the main detoxification pathways in the liver. If this process is impaired, taking methylated nutrients like methylcobalamin (as well as methylated folic acid or MTHF) can help. You can read more about this topic in the article “Methylation and Gene Mutation” .
- It acts in the cytosol to convert homocysteine (a potentially harmful compound) into methionine, which supports methylation processes necessary for neurotransmitter synthesis and to counteract behavioral and physiological responses induced by stress.
Adenosylcobalamin
- The most common form of vitamin B12 in the human body – it makes up nearly 70% of B12 and is an important intracellular coenzyme concentrated in mitochondria.
- Able to penetrate into mitochondria, where it provides significant support and protection in the production of ATP – the cell’s main energy currency. Insufficient levels of adenosylcobalamin lead to stress on mitochondria, which begin to prefer anaerobic (oxygen-free) functions over aerobic ones – this leads to an increase in lactic acid and other compounds such as uric acid, which can inhibit liver function and activate destructive immune processes.
- When adenosylcobalamin is deficient, the myelin sheath that surrounds and protects many of our nerve fibers begins to break down and become nonfunctional. Without functional myelin, communication in the nervous system occurs at an extremely slow rate instead of the typical high-speed response.
Better together
Methylcobalamin and adenosylcobalamin have related and complementary functions that they perform in different parts of the cell. Given their wide range of benefits, taking both forms, as recommended by Anthony William (who personally uses Vimergy® Organic Liquid Vitamin B12 with both cobalamin forms), is the best way to provide the necessary nutritional support the body needs to function optimally and maintain long-term health. Combining their powerful benefits and supporting nerve cells, methylation processes, DNA health, mood, behavioral responses, and overall well-being, these two forms are the true stars of the vital cobalamins.
Vimergy® Organic Liquid Vitamin B12 – a powerful formula of two active forms of vitamin B12
Vimergy® Organic Liquid Vitamin B12 contains this unique combination of two potent forms of vitamin B12. Both play a key role in maintaining our health and well-being. Until recently, scientists believed that the star of the cobalamins was cyanocobalamin, but this form requires the body to remove and detoxify a cyanide molecule in order to use the active part of the molecule in B12-dependent processes. This, of course, means extra work and metabolic processing.
Vimergy® Organic Liquid Vitamin B12 eliminates the need for this conversion by providing a potent formula containing both adenosylcobalamin and methylcobalamin – for complete vitamin B12 support. Offered in an easily absorbable and delicious liquid form, Vimergy® Organic Liquid Vitamin B12 is a leader in vitamin B12 supplements, providing effective, cell-targeted support for overall health.
Source: Vimergy.com blog – https://vimergy.com/blogs/news/what-are-the-benefits-of-b12
